Chromo domain-containing protein

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August undefined, 2024

Web66-115: 1.47e-21: CHROMO (CHRromatin Organization Modifier) domains and chromo shadow domains; Members of this group are chromodomains or chromo shadow domains; these are SH3-fold WebProteins containing a chromo shadow domain include Drosophila and human heterochromatin protein Su(var)205 (HP1); and mammalian modifier 1 and modifier 2. …

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WebOct 29, 1998 · CHD3 and CHD4 are highly related proteins that contain a number of putative functional domains, including PHD zinc-finger domains, chromo domains, and an ATPase/helicase domain which is similar to ... WebJun 1, 1998 · This family contains the functional homologues of PC and HP1, as well as other chromo-domain-containing proteins which also share additional motifs often found in nuclear proteins having potential roles in chromatin organisation [5]. HP1-like proteins are characterised by the presence of a related motif in the carboxy-terminal part, termed … black and blue union jack

UniProt

WebSep 29, 2010 · Chromo domain-containing protein 1 Molecule details › Chain: W Length: 800 amino acids Theoretical weight: 92.44 KDa Source organism: Saccharomyces cerevisiae Expression system: Escherichia coli BL21 (DE3) UniProt: Canonical: P32657 (Residues: 142-939; Coverage: 54%) Gene names: CHD1, SYGP-ORF4, YER164W … WebThe Ch romatin Or ganization Mo difier ( Chromo) domain is defined as a 30–70 amino acid residue protein module found in many proteins involved in the assembly of protein … Webchromo domain-containing protein (domain architecture ID 13036248) ... 3-9, enhancer-of-zeste, trithorax) domain-containing protein, and similar proteins. The SU(VAR)3-9 protein is the main chromocenter-specific histone H3-K9 methyltransferase (HMTase) in Drosophila where it plays a role in heterochromatic gene silencing. A chromodomain is a ... dave and adams twitter

Emerging Roles for Chromo Domain Proteins in Genome …

Chromodomain - an overview ScienceDirect Topics

WebHere we report the identities of two clo genes; one encodes histone H3.3 and the other, designated clo2, encodes a novel protein with significant homology to fission yeast Swi6p, human and Drosophila HP1 heterochromatin proteins, and other chromo domain-containing proteins. WebTHE “CHRomatin Organization MOdiﬁer” or CHROMO domain (CD) is a 40–55 amino acid domain found on a variety of proteins involved with chromatin structure for-mation, stability, remodeling, and gene expression regu-lation in eukaryotes. The protein families that contain CDs include the Chromo domain-Helicase-DNA-binding dave and adams store twitterWebChromo domain-containing protein LHP1 Gene LHP1 Status UniProtKB reviewed (Swiss-Prot) Organism Arabidopsis thaliana (Mouse-ear cress) Amino acids 445 Protein … black and blue under nail

"WebJan 1, 2001 · The mouse Mod1 chromo domain contains a hydrophobic groove, formed by the triple antiparallel β strands and carboxy-terminal α helix of the module. This hydrophobic groove is a candidate protein-interaction site and, on the basis of sequence conservation, is expected to be present in all chromo domains (including shadow domains). " - Chromo domain-containing protein

Chromo domain-containing protein

The chromo and SET domains of the Clr4 protein are essential for ...

WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. Proteomes. Protein sets from fully sequenced genomes. Annotation systems. Systems used to automatically annotate proteins with high accuracy: UniRule (Expertly curated rules) WebMar 1, 2024 · In general, chromo barrel domain is composed of five β-strands and one α-helix [36, 44], while chromodomain is made up by three β-strands and one α-helix [52-55], Tudor domain harbors four to five β-strands , PWWP domain contains five β-strands and one to six α-helices , and MBT, which forms a stable structure unit by using two to four ...

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WebSep 21, 2000 · Small deletions of the polycomb protein containing these residues lead to its delocalization in SL-2 ... L. J. et al. Structure of the chromatin binding (chromo) … WebSep 21, 2000 · Small deletions of the polycomb protein containing these residues lead to its delocalization in SL-2 ... L. J. et al. Structure of the chromatin binding (chromo) domain from mouse modifier protein.

WebOct 23, 2024 · We will highlight recent insights into the roles of chromo domain proteins in the regulation of heterochromatin and the spatial conformation of the genome as well as their functions in cell fate, fertility, small RNA pathways and … WebSep 5, 2001 · The chromo domain is a conserved protein fold of ~50 amino acids found in a variety of chromosomal proteins. The first recognition of the chromo domain motif came with the cloning of the Polycomb gene from Drosophila …

WebOct 14, 1997 · Chromo domains are found in a variety of proteins including the Drosophila melanogaster proteins HP1, which binds to heterochromatin at chromocenters and … WebThe MLL1 protein contains a SET domain, and chromosomal translocations involving the MLL1 gene occur in about 80% of infant leukemias. Another SET domain containing protein, RIZ1, has been implicated in a broad spectrum of human cancers. The RIZ gene maps to the distal short arm of chromosome 1, a region that is often rearranged in cancers.

WebOct 23, 2024 · Chromo domain proteins may function within a network of regulatory pathways that influence genome expression at local and global scales. (Bottom) Chromatin mechanisms play key roles in regulating cell …

WebProteins that possess a chromo domain are well-known for their roles in heterochromatin assembly and maintenance. The Heterochromatin Protein 1 (HP1) family, with a … dave and adam\u0027s card world codeWebFeb 11, 2004 · HP1 family proteins are adaptor molecules, containing two related chromo domains that are required for chromatin packaging and gene silencing. Here we present the structure of the chromo shadow domain from mouse HP1beta bound to a peptide containing a consensus PXVXL motif found in many HP1 binding partners. black and blue upholstery fabricWebThe CHD proteins are divided into 3 subfamilies based on unique protein domains. The CHD1/2 subfamily proteins contain a C-terminal DNA-binding domain and function in … dave and adams websiteWebAug 2, 2005 · The mammalian nuclear-receptor-binding SET-domain-containing protein (NSD1, a member of the SET2 family) has been found to play a crucial role in post-implantation development, ... Kouzarides T: Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature. 2001, 410: 120-124. 10.1038/35065138. black and blue usb portsWebMar 20, 2006 · The suvh and suvr alleles (in Columbia) contain mutations in genes related to KYP that contain SET domains predicted to methylate histone 3 . The mutants include a … dave and alex glastonburyWebHP1 has two conserved protein-protein interaction domains, a single N-terminal chromodomain (CD) which can bind to histone proteins via methylated lysine residues, … dave and a cameraWebOct 23, 2024 · We will highlight recent insights into the roles of chromo domain proteins in the regulation of heterochromatin and the spatial conformation of the genome as well as … dave and adam\\u0027s card world website